Lipoic acid bụ coenzyme dị na mitochondria nwere usoro molekul C8H14O2S2. Ọ dị ka vitamin ma nwee ike ikpochapụ free radicals nke na-ebute ịka nká na ọrịa ngwa ngwa. Lipoic acid na-abanye na sel mgbe etinyere ya na eriri afọ n'ime ahụ, ma nwee ma abụba-soluble na mmiri-soluble Njirimara. Lipoic acid bụ akụkụ nke ogige dị na vitamin B. Ọ bụ ihe na-eto eto maka yist na ụfọdụ microorganisms. Ọ na-arụ ọrụ coenzyme na sistemu enzyme multi-enzyme ma na-akwalite oxidative decarboxylation nke pyruvate ka acetic acid na oxidative decarboxylation nke α-ketoglutarate ka succinic acid. Transacylation etiti.

Dị ka coenzyme, lipoic acid na-ekere òkè na mmeghachi omume oxidative decarboxylation abụọ, ya bụ, na pyruvate dehydrogenase complex na α-ketoglutarate dehydrogenase complex, na-eme ka ọgbọ na nyefe nke acyl dị iche iche. Lipoic acid nwere ike ịnakwere otu acyl na otu acetyl nke pyruvate iji mepụta njikọ thioester, wee bufee otu acetyl na atom sọlfọ nke coenzyme A molecule. Dihydrolipoamide na-etolite otu prosthetic nwere ike oxidized site dihydrolipoamide dehydrogenase (chọrọ NAD +) iji nwetaghachi lipoamide oxidized. Alfa-lipoic acid nwere ihe mgbanaka disulfide nwere akụkụ ise nwere njupụta elektrọn dị elu, eletrọl dị ịrịba ama na ikike imeghachi omume na radicals efu. Ya mere, o nwere ihe antioxidant ma nwee ọrụ nlekọta ahụike dị elu yana uru ahụike (dịka imeju na-egbochi abụba na mbelata mmetụta cholesterol plasma).

A na-ejikarị lipoic acid egbochi shuga ịbanye na protein, ya bụ, ọ nwere mmetụta "na-egbochi glycation", ya mere ọ nwere ike ime ka ọ̀tụ̀tụ̀ shuga dị n'ọbara kwụsị ngwa ngwa. Ya mere, a na-ejibu ya dị ka vitamin iji meziwanye metabolism ma ndị ọrịa nwere ọrịa imeju na ọrịa shuga na-ewere ya. . Na-eme ka ọrụ imeju dị ike Lipoic acid nwere ọrụ na-eme ka ọrụ imeju sikwuo ike, n'ihi ya, a na-ejikwa ya dị ka ihe ngwọta maka nsị nri ma ọ bụ nsị ígwè n'oge mbụ.

Na-agbake site na nkụda mmụọ n'ihi na lipoic acid nwere ike ịbawanye ọnụego metabolism ume ma mee ka nri a na-eri ghọọ ume nke ọma, ọ nwere ike iwepụ ike ọgwụgwụ ngwa ngwa ma mee ka ahụ ghara ịgwụ ike. Na-emeziwanye Dementia Ihe ụmụ irighiri ihe mejupụtara nke lipoic acid dị ntakịrị, yabụ na ọ bụ otu n'ime nri ole na ole nwere ike iru ụbụrụ. Ọ na-akwadokwa ọrụ antioxidant na ụbụrụ, a na-ewerekwa ya dị ka ihe dị irè n'ịkwalite mgbaka.

Alfa lipoic acid bụ ọgwụ antioxidant dị ike. N'ihi na ọ na-agbaze mmiri na abụba-soluble. Nke a pụtara na ọ nwere mmetụta dịgasị iche iche, na-eru sel ọ bụla n'ime ahụ iji chebe akụkụ ahụ pụọ na mmebi radical free. Dị ka antioxidant, alfa lipoic acid nwere ike inye ụfọdụ uru ndị a: Na-enyere aka igbari ihe ndị na-egbu egbu dị ka mercury na arsenic n'ime imeju site n'ịbawanye mmepụta glutathione. Na-akwalite mmeghari nke ụfọdụ antioxidants, karịsịa vitamin E, C, glutathione na coenzyme Q10. Na-arụ ọrụ dị mkpa n'ịgbanwe glucose ka ọ bụrụ ike. Na-enyere aka ịkwalite ikike ncheta obere oge na ogologo oge.