Kedu ihe kpatara Pterostilbene dị ọcha ji bụrụ mgbakwunye kachasị mgbochi ịka nká?

Ka anyị na-aka nká, ahụ anyị na-enwe mgbanwe dị iche iche nke nwere ike iduga n'ịdalata ahụike na ume ike. Otú ọ dị, nchọpụta ndị sayensị chọpụtara n’oge na-adịbeghị anya emewo ka a ghọta otu ihe dị ike nke pụrụ inye aka ịlụso mmetụta ndị a nke ịka nká ọgụ. Banye pterostilbene dị ọcha, antioxidant eke eke na-enweta amara dị ka ihe mgbakwunye na-egbochi ịka nká.

Pterostilbene, nwa nwanne nne nke resveratrol a ma ama, dị obere na blueberries na mkpụrụ vaịn. Otú ọ dị, ihe ndị na-egbochi ịka nká ya na-eme ka mmepụta nke pterostilbene dị ọcha, na-enye ohere maka ntinye uche ma dị irè. Ka anyị leba anya n'ihe mere ogige a ji na-aghọ nhọrọ maka ndị na-achọ ịtụgharị elekere maka ịka nká.

Kedu ka Pterostilbene dị ọcha si alụ ọgụ maka ihe ịrịba ama nke ịka nká?

Pterostilbene dị ọcha na-egbochi ịka nká n'ọtụtụ ihu, na-eme ka ọ bụrụ mgbakwunye na-egbochi ịka nká na-agbanwe agbanwe ma dị irè. Nke a bụ ka ọ na-alụso akara dị iche iche nke ịka nká ọgụ:

Nchekwa ekwentị

N'ime obi ike pterostilbene nke mgbochi ịka nká bụ ikike ya ichekwa sel anyị. Ka anyị na-aka nká, mkpụrụ ndụ anyị na-akwakọba mmebi site na free radicals, na-eduga ná nrụgide oxidative. Pterostilbene na-arụ ọrụ dị ka antioxidant siri ike, na-ewepụ radicals ndị a na-emerụ ahụ ma na-echebe mkpụrụ ndụ anyị pụọ na mmebi. Nchekwa cellular a dị oke mkpa n'ịkwado ọrụ ntorobịa na ọdịdị.

Nchekwa DNA

DNA anyị, ụkpụrụ nke ndụ, adịghị egbochi mbibi nke oge. E gosipụtara Pterostilbene iji kwado iguzosi ike n'ezi ihe DNA, nwere ike ibelata usoro ịka nká na isi ya. Site n'ichekwa ihe mkpụrụ ndụ ihe nketa anyị, pterostilbene nwere ike inye aka ịnọgide na-arụ ọrụ cellular ma gbochie ọdịda metụtara afọ.

Nkwalite ọrụ ọgụgụ isi

Otu n'ime ihe ịrịba ama a na-ahụ anya nke ịka nká bụ mbelata ọgụgụ isi. Pterostilbene dị ọcha egosipụtala ihe ndị na-adịghị mma, nwere ike ịkwalite ebe nchekwa na ọrụ ọgụgụ isi. Site n'ịkwado ahụike ụbụrụ, pterostilbene nwere ike inye aka ịnọgide na-enwe mmetụta uche ka anyị na-aka nká.

Nkwado Cardiovascular

Ahụ ike obi bụ ihe dị mkpa na-echegbu anyị ka anyị na-etolite. Pterostilbene egosila nkwa n'ịkwado ahụike obi site n'inyere aka ịnọgide na-enwe ọbara mgbali elu na ọkwa cholesterol dị mma. Nkwado obi a dị oke mkpa maka ahụike zuru oke na ogologo ndụ.

Metabolic Balance

Ka anyị na-aka nká, metabolism anyị na-ebelatakarị, na-ebute ibu ibu na nsogbu ahụike metụtara ya. Pterostilbene nwere ike inye aka ịnọgide na-enwe nguzozi nke metabolic site n'ịkwado ọkwa shuga dị n'ọbara dị mma ma nwee ike inye aka na njikwa ibu.

Sayensị dị n'azụ ike mgbochi ịka nká nke Pterostilbene dị ọcha

Mmetụta mgbochi ịka nká nke pterostilbene dị ọcha abụghị naanị akụkọ ifo; nyocha sayensị kwadoro ha. Ka anyị nyochaa usoro ndị na-eme pterostilbene ka ọ bụrụ ihe na-egbochi ịka nká:

Nkwalite Sirtuin

E gosiputara Pterostilbene ka ọ rụọ ọrụ sirtuins, otu protein na-arụ ọrụ dị mkpa n'ịhazi ahụike na ogologo ndụ cellular. Site n'ịgbalite mkpụrụ ndụ ihe nketa "ogologo ndụ," pterostilbene nwere ike inye aka belata usoro ịka nká na ọkwa cellular.

Mbelata Mbufụt

Ọrịa na-adịghị ala ala bụ isi ihe na-akpata ịka nká na ọrịa ndị metụtara afọ. Pterostilbene dị ọcha egosipụtala ihe ndị na-egbochi mkpali dị ike, nwere ike ibelata usoro "ọkụ" a ma na-akwado ahụike na ogologo ndụ niile.

Ọrụ Mitochondrial

Mitochondria, nke a na-akpọkarị ụlọ ọrụ ike nke mkpụrụ ndụ anyị, na-ekere òkè dị mkpa na mmepụta ume na ahụike cellular. Ka anyị na-aka nká, ọrụ mitochondrial na-agbada. E gosipụtara Pterostilbene iji kwado ahụike mitochondrial, nwere ike imeziwanye ike ike yana ọrụ cellular n'ozuzu ya.

Nchekwa Telomere

Telomeres, mkpuchi mkpuchi na nsọtụ chromosomes anyị na-ebelata ka anyị na-aka nká. A na-ejikọta mkpirisi a na ịka nká cellular na ọrịa ndị metụtara afọ. Ụfọdụ ọmụmụ na-egosi na pterostilbene nwere ike inye aka chebe telomeres, nwere ike belata akụkụ a nke ịka nká.

Iwu Epigenetic

E gosiputara Pterostilbene ka ọ na-emetụta akara nrịbama epigenetic, nke bụ mgbanwe na okwu mkpụrụ ndụ ihe nke na-adịghị agụnye mgbanwe na usoro DNA dị n'okpuru. Site na imetụta ihe nrịbama epigenetic ndị a nke ọma, pterostilbene nwere ike inye aka idowe usoro okwu mkpụrụ ndụ ntorobịa.

Kedu ihe kpatara Pterostilbene dị ọcha ji arụ ọrụ Resveratrol?

Ọ bụ ezie na a na-eto resveratrol ogologo oge dị ka ihe mgbakwunye mgbochi ịka nká, pterostilbene dị ọcha na-apụta dị ka ihe ọzọ dị mma. Nke a bụ ihe kpatara pterostilbene nwere ike ịbụ nhọrọ kacha mma:

Enwetara bioavailability

Otu n'ime uru bụ isi nke pterostilbene karịa resveratrol bụ bioavailability ya dị elu. Pterostilbene na-abanye n'ime ahụ ngwa ngwa ma nọrọ na sistemụ ogologo oge, na-enye ohere maka uru na-adịgide adịgide. Nke a emelitere bioavailability pụtara na ọbụlagodi na obere doses, pterostilbene nwere ike inye mmetụta dị ike karịa resveratrol.

Nkwalite ekwentị emelitere

Ọdịdị kemịkalụ Pterostilbene na-enye ya ohere ịbanye n'ime membranes cell nke ọma karịa resveratrol. Nnweta cellular nke a na-eme ka ọ dịkwuo mma pụtara na pterostilbene nwere ike ime ngwa ngwa na-arụ ọrụ bara uru n'ime sel anyị, nke nwere ike ibute uru mgbochi ịka nká.

Nnukwu Metabolic kwụsie ike

Pterostilbene kwụsiri ike nke ukwuu karịa resveratrol, nke pụtara na ahụ anaghị agbaji ya ngwa ngwa. Nkwụsi ike a na-abawanye na-enye ohere ka pterostilbene kesaa n'ime ahụ ruo ogologo oge, nwere ike inye mmetụta mgbochi ịka nká na-adịgide adịgide.

Ọrụ Antioxidant dị ike

Ọ bụ ezie na ogige abụọ ahụ bụ antioxidants, ụfọdụ ọmụmụ na-egosi na pterostilbene nwere ike inwe ọrụ antioxidant dị ike karịa resveratrol. Ike a na-abawanye nwere ike ịtụgharị gaa na nchebe dị irè megide nrụgide oxidative na mmebi cellular metụtara afọ.

Oke uru bara ụba

Ọ bụ ezie na resveratrol na pterostilbene na-ekerịta ọtụtụ uru, pterostilbene egosila nkwa na mpaghara ndị ọzọ. Dịka ọmụmaatụ, pterostilbene egosipụtawo mmetụta ndị ọzọ na-apụta ìhè na ọrụ ọgụgụ isi na ahụike metabolic na ụfọdụ ọmụmụ, nwere ike ime ka ọ bụrụ ihe mgbakwunye mgbochi ịka nká.

mmechi

Pterostilbene dị ọcha pụtara dị ka onye na-agba ọsọ dị ike n'ụwa nke mgbakwunye mgbochi ịka nká. Ikike ya ịlụso ọtụtụ ihe ịrịba ama nke ịka nká ọgụ, yana bioavailability na ike ya dị elu ma e jiri ya tụnyere resveratrol, na-eme ka ọ bụrụ nhọrọ siri ike maka ndị na-achọ ịkwado ịka nká.

Site na nchekwa cellular na nchekwa DNA ruo nkwalite ọgụgụ isi na nkwado metabolic, pterostilbene na-enye ụzọ zuru oke maka mgbochi ịka nká. Ka nyocha na-aga n'ihu na-ekpughe uru nke onyinye a dị ịrịba ama, o doro anya na pterostilbene dị ọcha dị njikere ịghọ ihe mgbakwunye kachasị mma maka ịka nká. Ọ bụrụ na ị nwere mmasị n'iji ike mgbochi ịka nká nke pterostilbene dị ọcha, ọ dị mkpa ịhọrọ mgbakwunye dị elu site na isi iyi. Maka ozi ndị ọzọ gbasara pterostilbene dị ọcha na uru ọ nwere, biko kpọtụrụ anyị at ozi@sxrebecca.com.

References

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2. Estrela, JM, Ortega, A., Mena, S., Rodriguez, ML, & Asensi, M. (2013). Pterostilbene: Ngwa biomedical. Nlebanya dị egwu na sayensị ụlọ nyocha ahụike, 50(3), 65-78.

3. Kosuru, R., Rai, U., Prakash, S., Singh, A., & Singh, S. (2016). Nkwa na-ekwe nkwa ọgwụgwọ nke pterostilbene na nghọta usoro ya dabere na ihe akaebe izizi. Akwụkwọ akụkọ European nke Pharmacology, 789, 229-243.

4. Aguirre, L., Fernández-Quintela, A., Arias, N., & Portillo, MP (2014). Resveratrol: Usoro mgbochi oke ibu nke ime ihe. Molecules, 19 (11), 18632-18655.

5. Tsai, HY, Ho, CT, & Chen, YK (2017). Omume ndu na mmetụta molekụla nke resveratrol, pterostilbene, na 3'-hydroxypterostilbene. Akwụkwọ akụkọ nke nyocha nri na ọgwụ ọjọọ, 25 (1), 134-147.