Pterostilbene dị ọcha: Antioxidant siri ike maka ahụike ka mma

N'akụkụ ihe mgbakwunye ahụike eke, pterostilbene dị ọcha apụtala dị ka onye na-ese okwu siri ike, na-adọta uche maka njirimara antioxidant ya dị ịrịba ama na uru ahụike nwere ike. Ngwakọta a dị ike, nke nwere njikọ chiri anya na resveratrol, dị na blueberries na mkpụrụ vaịn, mana ọ dị ugbu a n'ụdị agbadoro dị ka ihe mgbakwunye nri. Ka anyị banye n'ime ụwa pterostilbene dị ọcha wee chọpụta ka ụlọ ọrụ antioxidant a nwere ike isi nye aka na ahụike na ọdịmma ka mma.

Ike Antioxidant nke Pterostilbene dị ọcha kọwara

Pterostilbene dị ọcha bụ polyphenol eke sitere na ezinụlọ stilbene nke ogige. Nhazi molekụla ya na-enye ya ohere ịlụso nrụgide oxidative ọgụ nke ọma karịa ọtụtụ antioxidants ndị ọzọ. Nchegbu oxidative na-eme mgbe enweghị ahaghị nhata n'etiti radicals free na antioxidants n'ime ahụ, na-ebute mmebi cellular na nsogbu ahụike dị iche iche.

Ike antioxidant nke pterostilbene dị ọcha dabere na ikike ya iwepụ radicals efu na-emerụ ahụ. Ụmụ irighiri ihe ndị a na-akwụsighị ike nwere ike imebi akụkụ cellular, gụnyere DNA, protein, na lipids. Site n'ịchụpụ radicals n'efu, pterostilbene na-enyere aka ichebe mkpụrụ ndụ site na mmebi oxidative, nke na-emetụta n'ọtụtụ ọrịa na ọnọdụ ndị metụtara afọ.

Nnyocha egosila na pterostilbene na-egosipụta bioavailability dị elu ma e jiri ya tụnyere nwanne nna ya, resveratrol. Nke a pụtara na ahụ nwere ike ịmịkọrọ ma jiri pterostilbene rụọ ọrụ nke ọma, nke nwere ike ibute uru ahụike ka ukwuu. A na-ekwu na bioavailability emelitere sitere na usoro ihe omimi nke pterostilbene, nke gụnyere otu methoxy abụọ na-eme ka ọ dịkwuo lipophilic ma kwụsie ike n'ime ahụ.

Ọzọkwa, pterostilbene dị ọcha egosipụtawo ihe mgbochi mkpali na ọmụmụ dị iche iche. Ọrịa na-adịghị ala ala bụ ihe a na-ahụkarị n'ọtụtụ ọrịa, gụnyere ọrịa obi, ọrịa shuga, na ọrịa cancer ụfọdụ. Site na ibelata mbufụt, pterostilbene nwere ike inye aka belata ihe ize ndụ nke ọnọdụ ndị a na-adịghị ala ala ma kwalite ahụike zuru oke.

Kedu ka Pterostilbene dị ọcha si akwado ịka nká?

Ka anyị na-aka nká, ahụ anyị na-enwekwu ike ịnweta nrụgide oxidative na mbufụt, nke nwere ike ime ka usoro ịka nká dịkwuo ngwa ma mee ka ọrịa ndị metụtara afọ dịkwuo elu. Pterostilbene dị ọcha na-enye ụzọ dị mma iji kwado ịka nká site na uru ya dị iche iche.

Otu n'ime isi ụzọ pterostilbene na-akwado ịka nká nke ọma bụ site na ịgbalite sirtuins, otu protein na-arụ ọrụ dị mkpa n'ịhazi ahụike na ogologo ndụ cellular. A na-akpọkarị Sirtuin dị ka "genes ogologo ndụ" n'ihi ikike ha nwere ịkwalite nrụzi na nhazi cellular. Site na ịgbalite protein ndị a, pterostilbene nwere ike inye aka belata usoro ịka nká na ọkwa cellular.

Pterostilbene egosila ikike ịkwado ahụike obi, ihe bụ isi na-eche ka anyị na-eme agadi. Nnyocha e mere egosiwo na ọ nwere ike inye aka belata ọbara mgbali elu, melite profaịlụ lipid, ma kwalite ọrụ endothelial. Mmetụta ndị a na-ejikọta ọnụ na-eme ka ahụike obi dịkwuo mma ma nwee ike belata ihe ize ndụ nke ọrịa obi.

Ọzọkwa, pterostilbene dị ọcha egosipụtawo ihe ndị na-adịghị mma, bụ ndị dị mkpa karịsịa n'ihe gbasara ịka nká. Ka mbelata ọgụgụ isi na-aghọ nchegbu na-eto eto na ịka nká, ikike pterostilbene iji chebe mkpụrụ ndụ ụbụrụ site na mmebi oxidative ma melite neuroplasticity na-enye olileanya maka ịnọgide na-arụ ọrụ ọgụgụ isi n'ime afọ ndị ọzọ.

Akụkụ ọzọ nke ịka nká ahụike nke pterostilbene na-akwado bụ ahụike metabolic. Nnyocha na-egosi na ngwakọta a nwere ike inye aka ịhazi ọkwa shuga dị n'ọbara ma melite mmetụta insulin. Mmetụta ndị a dị oke mkpa maka igbochi ma ọ bụ ijikwa ụdị ọrịa shuga 2, ọnọdụ na-agbasawanye karịa ka ọ dị afọ.

Pterostilbene dị ọcha nwere ike ịkwalite ọrụ ọgụgụ isi gị?

Uru nwere ọgụgụ isi nke pterostilbene dị ọcha emeela ka mmasị dị ukwuu na obodo sayensị. Nnyocha na-apụta na-egosi na antioxidant a dị ike nwere ike inwe mmetụta dị mma na ahụike ụbụrụ na ọrụ ọgụgụ isi.

Otu n'ime isi usoro site na nke pterostilbene nwere ike ịkwalite ọrụ ọgụgụ isi bụ site n'ibelata nrụgide oxidative na ụbụrụ. Ụbụrụ na-adị mfe karị na mmebi oxidative n'ihi oke ikuku oxygen na ọdịnaya lipid ya. Site na nkwụsị nke radicals free na ibelata nrụgide oxidative, pterostilbene na-enyere aka ichebe mkpụrụ ndụ ụbụrụ site na mmebi, nwere ike ichekwa ọrụ ọgụgụ isi ka oge na-aga.

Nnyocha egosiwokwa na pterostilbene nwere ike imeziwanye ebe nchekwa na ikike mmụta. N'ụdị anụmanụ, agbakwunyere pterostilbene ejikọtawo na nkwalite nchekwa ohere ọrụ yana ebe nchekwa ihe mara ihe. Nchọpụta ndị a na-egosi na pterostilbene nwere ike ịrụ ọrụ iji nọgide na-arụ ọrụ ọgụgụ isi ka anyị na-eme agadi.

Ọzọkwa, pterostilbene egosila ikike ịkwalite neuroplasticity, nke bụ ikike ụbụrụ ịmepụta njikọ akwara ọhụrụ na ime mgbanwe na ahụmahụ ọhụrụ. Ngwongwo a dị oke mkpa maka mmụta, nhazi ebe nchekwa, yana ngbanwe n'ozuzu ya. Site n'ịkwalite neuroplasticity, pterostilbene nwere ike inye aka mee ka ọrụ ọgụgụ isi dịkwuo mma na nkwụsi ike megide ịda mbà n'obi metụtara afọ.

Akụkụ ọzọ na-akpali akpali nke uru ọgụgụ isi nke pterostilbene bụ ikike ya ibelata mbufụt na ụbụrụ. Neuroinflammation na-amatawanye dị ka ihe na-akpata ọrịa neurodegenerative dị iche iche, gụnyere ọrịa Alzheimer. Site na ibelata mbufụt, pterostilbene nwere ike inye aka chebe megide ọnọdụ ndị a ma kwado ahụike ụbụrụ ogologo oge. Okwesiri iburu n'uche na n'agbanyeghi na nyocha nke mbu banyere uru uche nke pterostilbene na-ekwe nkwa, a chọkwuru ihe omumu mmadu iji kọwapụta mmetụta ya na ọrụ ụbụrụ n'ụzọ zuru ezu. Agbanyeghị, ihe akaebe dị ugbu a na-egosi na pterostilbene dị ọcha nwere ike ịbụ mgbakwunye bara uru na ndụ ahụike ụbụrụ.

mmechi

Pterostilbene dị ọcha pụtara dị ka antioxidant siri ike nwere uru ahụike dị ukwuu. Site na akụrụngwa antioxidant ya siri ike ruo na ikike ya n'ịkwado ịka nká na ọrụ ọgụgụ isi, pterostilbene na-enye ụzọ ebumpụta ụwa iji kwalite ọdịmma n'ozuzu ya. Ka nyocha na-aga n'ihu na-ekpughe ụdịdị dị iche iche nke uru pterostilbene, o doro anya na onyinye a nwere ọrụ na-ekwe nkwa n'akụkụ ihe mgbakwunye ahụike eke. Ọ bụrụ na ị na-atụle ịgbakwunye pterostilbene dị ọcha na usoro ahụike gị, ọ bụ ihe amamihe dị na ya ka gị na onye ọkachamara ahụike na-akpakọrịta iji hụ na ọ dabara maka mkpa gị. Maka ịdị mma dị elu pterostilbene dị ọcha na ndị ọzọ eke herbal extracts, nweere onwe gị iru anyị na ozi@sxrebecca.com.

References

1. McCormack D, McFadden D. "Pterostilbene na ọrịa cancer: nyochaa ugbu a." Akwụkwọ akụkọ nyocha ịwa ahụ. 2012.

2. Remsberg CM, et al. "Pharmacometrics nke pterostilbene: preclinical pharmacokinetics na metabolism, anticancer, mgbochi mkpali, antioxidant na analgesic ọrụ." Nnyocha nyocha nke Phytotherapy. 2008.

3. Riche DM, et al. "Nnyocha nchekwa site na nnwale ụlọ ọgwụ mmadụ na pterostilbene." Akwụkwọ akụkọ Toxicology. 2013.

4. Chang J, et al. "Pterostilbene dị ala, ma ọ bụghị resveratrol, bụ neuromodulator dị ike na ịka nká na ọrịa Alzheimer." Neurobiology nke ịka nká. 2012.

5. Kapetanovic IM, et al. "Pharmacokinetics, bioavailability ọnụ, na profaịlụ metabolic nke resveratrol na dimethylether analog, pterostilbene, na oke." Chemotherapy na ọgwụ ọgwụ. 2011.