Pterostilbene dị ọcha: Igodo iji lụso ọrịa shuga ọgụ na imelite mmetụta insulin.

N'ime mpaghara nke ogige eke nwere uru ahụike siri ike, pterostilbene dị ọcha apụtala dị ka onye na-atụ egwu n'ọgụ megide ọrịa shuga na ọrịa metabolic. Nke a dị ike antioxidant, nke nwere njikọ chiri anya na resveratrol mana enwere nkwalite bioavailability, adọtala uche nke ndị nyocha na ndị na-anụ ọkụ n'obi ahụike. Ka anyị leba anya n'otú pterostilbene dị ọcha nwere ike isi gbanwee njikwa ọrịa shuga yana mmetụta insulin.

Kedu ka Pterostilbene dị ọcha si ahazi ọkwa shuga ọbara?

Pterostilbene dị ọcha na-egosipụta ikike dị ịrịba ama n'ịhazi ọkwa glucose ọbara, na-eme ka ọ bụrụ ihe enyemaka bara uru na njikwa ọrịa shuga. Usoro ọrụ ya nwere ọtụtụ akụkụ, na-ezubere akụkụ dị iche iche nke metabolism glucose na ọrụ insulin.

Otu n'ime ụzọ pterostilbene si emetụta shuga dị n'ọbara bụ site n'ịkwalite mmetụta insulin. Ọ na-emezu nke a site na ịgbalite AMPK (AMP-activated protein kinase), enzyme dị mkpa na-achịkwa homeostasis ume cell. Site na mkpali AMPK, pterostilbene na-akwalite nnabata glucose na mkpụrụ ndụ akwara ma na-ebelata mmepụta glucose n'ime imeju, na-ebelata ọkwa shuga ọbara nke ọma.

Ọzọkwa, pterostilbene egosila ikike ichekwa mkpụrụ ndụ beta nke pancreatic, bụ ndị na-ahụ maka mmepụta insulin. Site n'ichekwa mkpụrụ ndụ ndị a dị mkpa na nrụgide oxidative na mbufụt, pterostilbene na-enyere aka ịnọgide na-enwe insulin kachasị mma, dị mkpa maka nhazi ọkwa glucose ọbara kwesịrị ekwesị.

Nnyocha egosiwokwa na pterostilbene nwere ike igbochi ụfọdụ enzymes na-etinye aka na mgbaze carbohydrate, dị ka α-amylase na α-glucosidase. Mgbochi a na-ebelata ndakpọ na nnabata nke carbohydrates, na-ebute mmụba nke nta nke nta na ọkwa shuga ọbara mgbe nri gasịrị.

Njirimara antioxidant nke pterostilbene na-ekere òkè dị ukwuu na mmetụta na-achịkwa shuga ọbara ya. Nchegbu oxidative bụ isi ihe na-enye aka na nguzogide insulin na ọganihu ọrịa shuga. Site na iwepu radicals na-emerụ ahụ na ibelata mbufụt, pterostilbene na-enyere aka belata mmebi nke cellular nke nwere ike ibute ọrụ insulin na-emebi emebi yana metabolism glucose.

Pterostilbene dị ọcha vs. Metformin: Nhọrọ eke?

Ka a na-achọ ọgwụgwọ ọrịa shuga dị irè na nke a na-anabata nke ọma, ọtụtụ na-atụgharị gaa n'ụdị ọzọ nke ọgwụ ndị a na-ahụkarị. Pterostilbene dị ọcha atụnyere metformin, otu n'ime ọgwụ a na-enyekarị maka ụdị ọrịa shuga 2. Ọ bụ ezie na ogige abụọ ahụ na-egosi nkwa na njikwa ọkwa shuga dị n'ọbara, ha dị iche n'akụkụ dị iche iche.

Metformin na-arụ ọrụ n'ụzọ bụ isi site na ibelata mmepụta glucose na imeju yana imeziwanye mmetụta insulin na anụ ahụ dị n'akụkụ. Ọ nwere ndekọ ndekọ ogologo oge nke ịdị irè na nchekwa, nke ọtụtụ iri afọ nke iji ụlọ ọgwụ kwadoro. Otú ọ dị, ụfọdụ ndị ọrịa na-enweta mmetụta dị n'ime eriri afọ ma ọ bụ na-egbochi ya n'ihi nsogbu ọrụ akụrụ.

Pterostilbene dị ọcha, n'aka nke ọzọ, na-enye uru dị iche iche sara mbara. E wezụga mmetụta ya na-ebelata glucose, pterostilbene na-etu ọnụ nwere ike antioxidant na mgbochi mkpali Njirimara. Uru ndị a ọzọ nwere ike inye nchebe pụọ na nsogbu ndị na-adịte aka nke ọrịa shuga, dị ka ọrịa obi na ọrịa neuropathy.

Otu uru pụtara ìhè nke pterostilbene bụ bioavailability ya dị elu ma e jiri ya tụnyere ogige ndị ọzọ sitere n'okike dị ka resveratrol. Esemokwu dị iche iche nke na-eme ka pterostilbene dịkwuo lipophilic na-enye ohere maka ịmịnye nke ọma na ogologo ndụ ọkara n'ime ahụ, nke nwere ike ịkpata mmetụta na-adịgide adịgide.

Ọ bụ ezie na a mụọla metformin nke ọma na nnwale ụlọ ọgwụ buru ibu, nyocha na pterostilbene n'ihe gbasara mmadụ ka nọ na mmalite ya. Agbanyeghị, ọmụmụ izizi egosila nsonaazụ na-ekwe nkwa. Dịka ọmụmaatụ, nnwale a na-achịkwaghị achịkwa, nke kpuru ìsì abụọ, ebe a na-achịkwa ebebo nke e bipụtara n'akwụkwọ akụkọ Nutrients chọpụtara na mgbakwunye pterostilbene mere ka njikwa glycemic dị mma na profaịlụ lipid na ndị okenye nwere cholesterol LDL dị elu.

Ọ dị mkpa ịmara na mgbe ahụ pterostilbene na-egosi ikike dị ukwuu dị ka ihe ọzọ sitere n'okike, e kwesịghị ile ya anya dị ka onye na-anọchi anya ọgwụ ndị a na-enye ọgwụ na-enweghị ịgakwuru onye ọkachamara ahụike. Ụzọ kachasị mma nwere ike ịgụnye itinye pterostilbene dị ka akụkụ nke atụmatụ nlekọta ọrịa shuga zuru oke, nke nwere ike inye ohere maka mbelata dose nke ọgwụ ọdịnala.

Ụzọ kacha mma iji were Pterostilbene dị ọcha maka nlekọta ọrịa shuga

Ịgbakwunye pterostilbene dị ọcha n'ime usoro nlekọta ọrịa shuga gị chọrọ nlezianya nyochaa usoro onunu ogwu, oge, na ụdị mgbakwunye. Ọ bụ ezie na nyocha na-aga n'ihu iji guzobe ụkpụrụ nduzi doro anya, ihe akaebe dị ugbu a na-enye ụfọdụ nghọta maka ịkwalite oriri pterostilbene maka njikwa shuga ọbara.

Usoro onunu ogwu bụ ihe dị mkpa n'ịkwalite uru nke pterostilbene. Ọmụmụ ihe ejirila ọtụtụ doses, nke na-adịkarị n'etiti 50-250 mg kwa ụbọchị. Ebe mmalite na-emekarị bụ 100 mg kwa ụbọchị, nke enwere ike gbanwee dabere na nzaghachi onye ọ bụla yana n'okpuru nduzi nke onye nlekọta ahụike. Ọ dị mkpa ịmara na ọ bụghị mgbe niile ka ọtụtụ ihe adịghị mma, na ịchọta nguzozi ziri ezi bụ isi ihe na-eme ka uru dịkwuo elu ma na-ebelata mmetụta ndị nwere ike ime.

Oge mgbakwunye pterostilbene nwere ike imetụta arụmọrụ ya. Nnyocha ụfọdụ na-egosi na ị were pterostilbene na nri nwere ike ime ka nnabata ya dịkwuo elu, ọkachasị mgbe ejiri isi iyi nke abụba dị mma rie ya. Usoro a na-enye ohere nke pterostilbene ọdịdị lipophilic, nwere ike imeziwanye bioavailability ya.

Pterostilbene dị ọcha dị n'ụdị dị iche iche, gụnyere capsules, powders, na mmiri mmiri. Capsules na-enye ntụsara ahụ dị mma na nke ziri ezi, na-eme ka ha bụrụ nhọrọ a ma ama maka mgbakwunye kwa ụbọchị. Ntụ ntụ na-enye mgbanwe na doses na enwere ike itinye ya ngwa ngwa n'ime smoothies ma ọ bụ ihe ọṅụṅụ ndị ọzọ. Mwepụta mmiri mmiri nwere ike na-enye nnabata ngwa ngwa mana ọ chọrọ nha nke ọma iji hụ na a na-eme ya nke ọma.

Maka ndị na-achọ ịbawanye uru nke pterostilbene, ijikọta ya na ogige ndị ọzọ eke nwere ike inye mmetụta synergistic. Dịka ọmụmaatụ, ijikọ pterostilbene na quercetin ma ọ bụ resveratrol egosila nkwa n'ịkwalite Njirimara mgbochi mkpali na antioxidant. Otú ọ dị, ọ dị mkpa ka gị na onye ọkachamara na-ahụ maka ahụike kpọtụrụ ya tupu ijikọta ihe mgbakwunye iji zere mmekọrịta ndị nwere ike ime.

Nkwenye bụ isi mgbe ị na-etinye pterostilbene n'ime usoro nlekọta ọrịa shuga gị. Mmetụta ngwakọta ahụ na nhazi shuga ọbara yana mmetụta insulin nwere ike iwepụta oge iji gosipụta nke ọma. Ịnọgide na-enwe usoro mgbakwunye mgbe niile, yana nri ziri ezi na mmega ahụ mgbe niile, nwere ike inye aka kwalite uru pterostilbene maka njikwa ọrịa shuga.

mmechi

Pterostilbene dị ọcha na-anọchite anya oke na-atọ ụtọ na njikwa ọrịa shuga eke na njikarịcha ahụike metabolic. Ngwongwo ya pụrụ iche, gụnyere mmụba bioavailability na mmetụta dị iche iche na metabolism glucose, debe ya dị ka ngwá ọrụ bara uru n'ọgụ megide ọrịa shuga na nguzogide insulin. Ka nyocha na-aga n'ihu ịkọwapụta ikike nke onyinye a dị ịrịba ama, itinye pterostilbene dị ọcha n'ime usoro nlekọta ọrịa shuga zuru oke nwere ike inye olileanya ọhụrụ maka ndị na-achọ imeziwanye ahụ ike metabolic ha n'ụzọ nkịtị.

Maka ozi ọzọ na pterostilbene dị ọcha na ihe ndi ozo sitere n'okike, biko kpọtụrụ anyị at ozi@sxrebecca.com. Ndị otu ndị ọkachamara anyị dị njikere inyere gị aka n'ịchọpụta uru nke ogige okike ndị a dị ike maka ebumnuche ahụike na ahụike gị.

References

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