Piperine ntụ ntụ: Ihe nzuzo iji nweta nkwalite bioavailability na mgbakwunye

N'ime ụwa nke ihe mgbakwunye nri, bioavailability bụ ihe dị oke mkpa na-ekpebi ka ahụ gị nwere ike isi nweta ma were nri. Banye piperine ntụ ntụ, ihe dị ike nke sitere na ose ojii na-enweta nlebara anya maka ikike dị ịrịba ama ya iji welie nnabata nke nri dị iche iche na ogige. Bọọgụ blọgụ a na-abanye n'ime ụwa na-adọrọ adọrọ nke piperine ntụ ntụ ma chọpụta otú ọ ga-esi gbanwee usoro mgbakwunye gị.

Kedu ka ntụ ntụ Piperine si eme ka nri na-edozi ahụ pụta?

Piperine, ihe na-arụ ọrụ na ose ojii, ejirila ọtụtụ narị afọ mee ihe na ọgwụgwọ ọdịnala. Nnyocha ọgbara ọhụrụ ekpughere ikike ya dị egwu iji welie bioavailability nke ọtụtụ nri na ogige. A na-ekesa ihe omume a n'ọtụtụ usoro:

- Ikike nke eriri afọ abawanyela: Piperine nwere ikike iwelite permeability nke membranes sel eriri afọ, nke na-eme ka nnabata nke nri dị mma site na tract digestive.

- Mgbochi nke ọgwụ-metabolizing enzymes: Site n'igbochi ụfọdụ enzymes na imeju na eriri afọ, piperine na-ebelata nkwụsị nke metabolic nke ogige dị iche iche, na-eduga na ọnụnọ ogologo oge nke ihe bara uru n'ime ọbara.

- Ịkwalite ndị na-ebugharị Amino Acid: Piperine ntụ ntụ na-eme ka protein ndị njem na-ebugharị nke na-enyere aka ịkwaga amino acid na nri ndị ọzọ dị mkpa n'ofe cell membranes, na-eme ka ha dị maka ahụ.

- Mmetụta Thermogenic: Mmetụta dị nro na-emepụta okpomọkụ nke piperine nwere ike ime ka ọbara na-erugharị na usoro nri nri, nwere ike ịkwalite nnabata nri na ịkwalite ahụike nri nri. Nke a thermogenic edinam na-akwado ịrụ ọrụ nke ọma nnyefe nke nri ofụri idem.

Usoro ndị a na-arụ ọrụ synergistically iji kwalite bioavailability nke ọtụtụ nri nri, gụnyere vitamin, mineral, na phytochemicals. Dịka ọmụmaatụ, ọmụmụ egosila na piperine nwere ike ịkwalite mmịnye nke selenium, beta-carotene, curcumin, na coenzyme Q10, n'etiti ndị ọzọ.

Sayensị dị n'azụ Piperine na uru ahụike ya

Ewezuga ọrụ ya n'ịkwalite nnabata nri, piperine ntụ ntụ na-akwado ọtụtụ uru ahụike nke nyocha sayensị kwadoro:

- Mmetụta mgbochi mkpali: Piperine na-egosipụta ihe mgbochi mkpali siri ike, nke nwere ike inye aka n'ibelata mgbaàmà jikọtara na mbufụt na-adịghị ala ala na ịkwalite ahụike zuru oke.

- Ọrụ Antioxidant: Dị ka antioxidant siri ike, piperine na-enyere aka ịlụso radicals free emerụ ahụ ọgụ, nwere ike ibelata nrụgide oxidative na igbochi mmebi cellular, nke na-akwado ahụike ogologo oge.

- Nkwalite ọgụgụ isi: Nnyocha na-egosi na piperine nwere ike inye aka melite ọrụ ọgụgụ isi ma nwee ike rụọ ọrụ nchebe megide ọrịa neurodegenerative, na-akwado ahụike ụbụrụ na nghọta uche.

- Nkwado maka Ahụike Metabolic: Nnyocha na-egosi na piperine nwere ike inye aka n'ịkwado metabolism dị mma, nwere ike inye aka na njikwa ibu site na imetụta nhazi na ọrụ nke mkpụrụ ndụ abụba.

- Nkwado ahụike digestive: Achọpụtala Piperine na-akpali mmepụta nke enzymes digestive, nke nwere ike ime ka ọrụ nke usoro nri digestive na-arụ ọrụ zuru oke ma melite absorption nke nri, na-enye aka na ahụike nri nri ka mma.

The multifaceted uru nke piperine ntụ ntụ mee ka ọ bụrụ ihe na-adọrọ mmasị maka ndị na-achọ ịkwalite ahụike ha na usoro mgbakwunye. Ikike ya iji welie bioavailability nke nri ndị ọzọ na-emepụta mmetụta synergistic nke nwere ike ịbawanye mmetụta nke mgbakwunye nri gị.

Ụzọ kachasị mma iji jiri ntụ ntụ Piperine mee mmetụta kachasị

Iji nweta ikike zuru oke nke piperine ntụ ntụ, tụlee atụmatụ ndị a:

- Jikọọ na nri na-agbaze abụba: Jikọta piperine na vitamin soluble abụba (A, D, E, K) na ogige dị ka curcumin iji mee ka mmịpụta ha dịkwuo mma, ebe piperine nwere ike ime ka bioavailability nke nri ndị a dịkwuo mma, na-eme ka arụmọrụ ha dịkwuo mma.

- Tinye n'ime usoro mgbakwunye gị: Chọọ ihe mgbakwunye nwere piperine ma ọ bụ ose ojii, ma ọ bụ tụlee ịgbakwunye mgbakwunye piperine kwụ ọtọ na usoro gị kwa ụbọchị maka uru ahụike ọzọ.

- Oge bụ isi: Iji mee ka mmịpụta dịkwuo elu ma belata ihe ize ndụ nke ahụ erughị ala afọ, were ihe mgbakwunye nwere piperine n'akụkụ nri. Nke a na-enyere aka ịkwalite oriri na-edozi ahụ ma na-ebelata ihe ndị nwere ike ime ka mgbari nri.

- Kpachara anya maka usoro onunu ogwu: Ọ bụ ezie na usoro ọgwụgwọ dị mma nwere ike ịdịgasị iche dabere na mkpa onye ọ bụla, ọtụtụ ọmụmụ na-atụ aro ka a na-eri 5-20 mg kwa ụbọchị. piperine ntụ ntụ. Ọ dị mkpa ka gị na onye ọkachamara na-ahụ maka ahụike gakwuru ka ị chọpụta dose kwesịrị ekwesị maka mkpa gị.

- Chọpụta ihe eji eme nri nri: Tinye ose ojii n'ala ọhụrụ na nri gị ka ị nweta uru ebumpụta ụwa nke piperine. Buru n'uche na isi nri nwere ike ibelata ọdịnaya piperine, n'ihi ya, ọ ka mma ịgbakwunye ose mgbe esichara nri iji jigide mmetụta bara uru.

Ọ dị mkpa ịmara na ọ bụ ezie na piperine nwere ike ime ka nnabata nke ọtụtụ ogige bara uru, ọ nwekwara ike ịbawanye mmịnye nke ọgwụ ụfọdụ. Gị na onye na-ahụ maka ahụike na-akpakọrịta mgbe niile tupu ị gbakwunye mgbakwunye piperine na usoro gị, ọkachasị ma ọ bụrụ na ị na-ewere ọgwụ ndenye ọgwụ.

mmechi

Piperine ntụ ntụ pụtara dị ka ihe okike dị ịrịba ama nke nwere ike ịkwalite bioavailability nke ọtụtụ nri na mgbakwunye. Site n'itinye piperine n'ime usoro mgbakwunye gị, ị ga-enwe ike ịbawanye uru nke itinye ego na-edozi ahụ ma kwado ahụike na ịdị mma n'ozuzu ya.

Ka nyocha na-aga n'ihu na-ekpughe ikike nke piperine, o doro anya na nke a dị umeala n'obi sitere na ose ojii nwere ọtụtụ ihe ọ ga-enye n'akụkụ sayensị na-edozi ahụ na mgbakwunye. Ma ị na-achọ ịkwalite irè nke mgbakwunye gị ugbu a ma ọ bụ nyochaa ụzọ ọhụrụ maka ịkwalite ahụike gị, piperine ntụ ntụ kwesịrị nlebara anya nke ọma.

Maka ịdị mma dị elu piperine ntụ ntụ na ndị ọzọ eke herbal extracts, kọntaktị Shaanxi Rebecca BioTechnology Co., Ltd ozi@sxrebecca.com. Ndị otu ndị ọkachamara anyị raara onwe ha nye inye ihe mgbakwunye ihe mgbakwunye sayensị na-akwado maka ahụike na ahụike gị.

References

1. Kesarwani, K., & Gupta, R. (2013). Ihe nkwalite bioavailability sitere na ahịhịa: nyocha. Akwụkwọ akụkọ Asia Pacific nke Tropical Biomedicine, 3(4), 253-266.

2. Fernández-Lázaro, D., Mielgo-Ayuso, J., Córdova Martínez, A., & Seco-Calvo, J. (2020). Ígwè na mmega ahụ́: ndị na-akwalite bioavailability, Njirimara nke ose ojii (bioperine) na ngwa nwere ike. Nri nri, 12(6), 1886.

3. Majeed, M., Badmaev, V., & Rajendran, R. (2019). Bioavailability nke curcuminoids sitere na mpụta turmeric bioavailable nwere curcuminoids ọkọlọtọ na mmanụ turmeric dị mkpa na ndị ọrụ afọ ofufo nwere ahụike. Akwụkwọ akụkọ nri ọgwụ, 22 (8), 835-842.

4. Jain, S., Patel, JR, & Patel, NA (2018). Piperine: Nlebanya zuru oke nke ụzọ nke ikewapụ, ịdị ọcha, na ihe ndị dị ndụ. Nlebanya pere mpe na Chemistry ọgwụ, 18(17), 1407-1414.

5. Bhardwaj, RK, Glaeser, H., Becquemont, L., Klotz, U., Gupta, SK, & Fromm, MF (2002). Piperine, bụ isi ihe mejupụtara ose ojii, na-egbochi P-glycoprotein mmadụ na CYP3A4. Akwụkwọ akụkọ nke Pharmacology and Experimental Therapeutics, 302 (2), 645-650.